Showing posts with label 2011 Germany E. coli O104:H4 outbreak. Show all posts
Showing posts with label 2011 Germany E. coli O104:H4 outbreak. Show all posts

Tuesday, May 19, 2009

Nearly five billion doses of swine flu vaccine possible: WHO

Time is GMT + 8 hours
Posted: 20-May-2009 01:36 hrs

090520-0136hrs An epidemiologist leaves a hospital in Panama City. Production of 4.9 billion doses of a swine vaccine a year would be possible, according to an extract of a World Health Organisation forecast presented to vaccine makers that was seen by AFP.

Production of up to 4.9 billion doses of a swine flu vaccine a year would be possible, according to a World Health Organisation forecast presented to vaccine makers on Tuesday.

The WHO is counting on output of 94.3 million doses a week if full-scale production is launched, according to the presentation made to pharmaceutical companies at a meeting in Geneva, part of which was seen by AFP.

The document was based on recommendations made by a working group of vaccine experts.

"That is a very optimistic maximum capacity," WHO Director General Margaret Chan told journalists after the meeting.

Two doses might be needed for immunity from swine flu, depending on the outcome of research, she said.

"Clearly there are a lot of unanswered questions," she added.

The Swiss pharmaceutical group Novartis said it had received samples of the new A(H1N1) virus and was awaiting the UN health agency's go ahead to begin producing a vaccine.

About 30 vaccine makers from 19 industralised and developing countries were invited by the WHO to the one-hour meeting to discuss production of a vaccine against swine flu.

Ban told the WHO's assembly afterwards that partnerships with the private sector would be "absolutely vital".

"Solidarity in the face of this particular outbreak must mean that all have access to drugs and vaccines," he told the WHO's 193 member states. "It means that virus samples and data are shared."

A key issue for the meeting was the cost of the vaccine and its availability in the most vulnerable poor countries, officials said.

The WHO was seeking funding from the World Bank, the Global Fund for AIDS, Tuberculosis and Malaria, UNITAID and other foundations to help finance vaccine supply in poor nations, said Chan.

But just before the assembly, it failed to resolve a long-running dispute on the sharing of virus samples from patients to help develop pandemic vaccines.

Indonesia, one of the countries hit by H5N1 bird flu, raised concerns two years ago about access to subsequent commercially developed vaccines for people in poor countries.

The WHO is also weighing up the the risks of halting production of the seasonal flu virus to free up production capacity for a swine flu vaccine.

Chan reiterated that for the moment there was still a need to give priority to seasonal flu vaccine, especially in the southern hemisphere where the winter flu season is just starting.

A Novartis spokesman said if the company started producing a swine flu vaccine it could face a difficult dilemma: where to focus its production, given the potentially different needs in each hemisphere.

At the opening of the WHO's annual assembly here, Chan warned health ministers about the risk the swine flu virus would pose for low- and middle-income countries. They carry 85 percent of the global burden of chronic disease.

"The implications are obvious," she said. "The developing world has, by far, the largest pool of people at heightened risk for severe and fatal H1N1 infections."
The new A(H1N1) virus causes symptoms that are no more severe than those of seasonal flu, according to evidence gathered by scientists so far.

But like all influenza infections, experts say those who are already ill or suffering chronic ailments are in greater danger, and in wealthy nations they are advised to take the annual flu vaccination.

Many of the 74 swine flu deaths recorded by the WHO outside Mexico have involved people who were already weakened by other ailments. — AFP

From TODAYOnline.com; see the source article here.

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Monday, May 4, 2009

Swine flu could return 'with a vengeance': WHO

AFP – Tuesday, May 5


MEXICO CITY (AFP) - – The head of the World Health Organisation warned on Monday that swine flu could return with a vengeance despite Mexico's President Felipe Calderon insisting his country has contained the epidemic.

WHO chief Margaret Chan said in a newspaper interview that a second wave of the virus "would be the biggest of all outbreaks the world has faced in the 21st century", puncturing optimism emanating from the epicentre of the outbreak.

The diplomatic damage from the epidemic also reverberated with China denying it had discriminated against Mexican nationals after dozens were placed under quarantine over the weekend despite showing no signs of the flu.

Twenty-five people have died from swine flu, according to the WHO which estimates there are nearly 900 cases in 20 countries . All but one of the deaths have been in Mexico.

Calderon said Mexico had managed "to contain the epidemic" and was now "in a position to overcome" the A(H1N1) virus.

His health minister, Jose Angel Cordova, told a news conference the epidemic peaked between April 23 and 28 and was "in its phase of decline".

But Chan said the end of the flu season in the northern hemisphere meant that while any initial outbreak could be milder, a second wave could be more lethal, reflecting a pattern first seen with the 1918 Spanish flu pandemic that killed up to 50 million people worldwide.

"We hope the virus fizzles out, because if it doesn't we are heading for a big outbreak," Chan told the Financial Times, adding that it could re-emerge in the months ahead "with a vengeance".

"I'm not predicting the pandemic will blow up, but if I miss it and we don't prepare, I fail. I'd rather over-prepare than not prepare."

The UN agency last week raised its alert level to five, indicating that a global pandemic is imminent.

More countries are confirming cases every day with Italy and Colombia becoming the latest to join the list, while France announced two new confirmed cases.

Japan on Monday tripled the number of quarantine officers at Tokyo's Narita airport to try to detect cases at the start of a key holiday week.
And in the United States, the only other country to have recorded a death from the virus, officials said that more than half the 50 states had now confirmed cases.

US Health and Human Services Secretary Kathleen Sebelius echoed Chan's warning that the real test would come when the winter influenza season hits in a few months.

"One of the things that we know is that even if this current situation seems to be lessening, if we are cautiously optimistic, we really don't know what's going to happen when real flu season hits (together) with H1N1 virus," she told CBS television.

In China, the centre of the 2003 SARS outbreak, authorities have been accused of discriminating against Mexican nationals in its bid to stop the disease in its tracks.

Although no cases of swine flu have been reported on the Chinese mainland, one Mexican who stayed in a hotel in Hong Kong has tested positive.

A Mexican embassy official said there were nearly 70 of his compatriots had been quarantined across China including in Beijing, Shanghai and the southern city of Guangzhou even though they had demonstrated no flu symptoms.

China's foreign ministry spokesman Ma Zhaoxu said in a statement: "The relevant measures are not directed at Mexican citizens and are not discriminatory."

Myrna Elisa Berlanga, 31, a Mexican tourist who arrived in China on Saturday, questioned why she was being quarantined since no one on her flight from the United States had the virus.

"Right now we are tired of being confined, not knowing what will happen with us," she told AFP by phone from the hotel near Beijing's airport where she and nine other Mexicans are being isolated.

From Yahoo! News; source article is here.