Showing posts with label Screening (medicine). Show all posts
Showing posts with label Screening (medicine). Show all posts

Thursday, September 8, 2011

A new risk marker for heart diseases

By Sharon See | Posted: 30 July 2011

A screening test that measures C-Reactive Protein levels in blood can be a more accurate indicator of possible heart diseases
SINGAPORE: Obesity, high cholesterol and smoking are some well-known factors that can lead to heart disease.

But there is another measure that can push a group of seemingly-healthy people into the high risk category.

Doctors said C-Reactive Protein (CRP) levels can be a more accurate indicator of possible heart diseases.

A screening test that measures CRP in blood can be a more accurate indicator, say doctors.

While such screening tests are not for everyone, those above the age of 40 who go for regular screening may benefit most.

Associate Professor Tai E Shyong, Senior Consultant & Head, Endocrinology, National University Hospital, said: "The Singapore recommendation is that everybody above the age of 40 should have a cholesterol measure, should have a blood pressure measure, should have a blood sugar measure.

"Then you can combine all these information to a score that tells you the chances of having a heart attack the next ten years is five per cent, 15 per cent, 20 per cent. That's the first thing you have to do. You got to do a risk assessment. What we're saying is that those people who're high risk, they need treatment.

"Those people at low risk probably don't need a drug, so there's no decision to be made. It's specifically the people who are in between 10 and 20 per cent. If you measure CRP, and the CRP is high, you might be a little bit more aggressive with drug therapy."

Cholesterol drugs or statins may now be prescribed for those at moderate risk but a high CRP.

Currently, doctors prescribe such drugs known as statins to those with heart disease or who are at high risk.

Studies by European researchers suggests their risk of stroke and heart attack can be cut by about 50 per cent.

However, there are side effects to statins, such as headache, muscle pain, abdominal pain, weakness and nausea.

For this reason, Associate Professor Tai said it is not cost effective for low risk individuals to take statins to lower the risk of heart disease as the side effects may outweigh the benefits.

But he added the best prevention is still to maintain a healthy lifestyle.

"One of the things that is important to remember is that lifestyle modification can bring down CRP. In fact, one of the most effective ways to do it is to lose weight. The other thing that's important is that, if you smoke, you got to stop smoking."

- CNA/fa



Taken from ChannelNewsAsia.com; source article is below:
A new risk marker for heart diseases


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Friday, March 26, 2010

EYES: WINDOWS TO ONE'S HEALTH

Human eye cross-sectional view. Courtesy NIH N...Image via Wikipedia
The Eye Care Revolution: Prevent and Reverse Common Vision ProblemsA news article taken form TODAYOnline.com, Tuesday, 23-Mar-2010

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SINGAPORE - The eye says a lot about the body. For example, damaged blood vessels in the retina can warn of damage in the brain, heart or kidneys.

In a few months, four polyclinics will use a retina imaging service - taking a picture of patients' eyes - to screen for conditions like diabetic retinopathy, glaucoma and heart diseases.

The three are in Outram, Bukit Merah and Clementi, while the fourth will be made known later.

Cholesterol and diabetes levels have traditionally been key indicators of cardiovascular diseases. But these methods fail to detect half the patients who are at high-risk.

This is set to change, however, with the pilot project which will focus on glaucoma.

Glaucoma is one of the more important diseases to be picked up, as 90 per cent of the people who have it are not aware of it, said Professor Wong Tien Yin, director of the Singapore Eye Research Institute.

The imaging technology has shown that it is able to pick up glaucoma between 80 and 90 per cent of the time, he said. In future, there will also be more "accurate information" so that doctors can decide whether surgery should be done.

The information will also be useful for patients who can decide what they should do.

An initial 3,000 patients will be selected for the retina imaging service when they go for their normal health screening.

Their eye images will be sent to the new Singapore Advanced Imaging Laboratory for Ocular Research (Sailor) for analysis.

The preliminary screening will catch those who are at high-risk, but have not yet been detected, said Prof Wong, who is also Sailor's co-director.

The retinal image at the polyclinics will cost between $6 and $15 compared to "hundreds" at a specialist. The advantage of the service is that it is low cost, uses readily-available technology and can serve as a "first round" of detection for those who might need further tests or specialist care, said Prof Wong.

There are also plans to tie up with healthcare clusters and to take this model abroad although a cost-effective study has to be done before the programme is expanded.

More than 3 per cent of the population aged 40 and above are diagnosed with glaucoma, a group of disorders which have in common an increase in the pressure inside the eye. Too high a pressure damages the optic nerve, and blindness can occur in severe cases.

While no estimates are available for Singapore, Prof Wong said such early detection and prevention is estimated to save some US$600 million ($839 million) for the United States annually.

Sailor, which cost more than $5 million to set up, was launched yesterday at the second Asia-Pacific Ocular Imaging Symposium yesterday.

It is a collaboration between A*Star's Institute for Infocomm Research and the Singapore Eye Research Institute, and is the third centre for eye research in the Fusionopolis-Biopolis science hub.
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