Showing posts with label Neurology. Show all posts
Showing posts with label Neurology. Show all posts

Monday, August 15, 2011

Parkinson's patients show high melanoma risk

Posted: 07 June 2011

A cancer patient receives radiation treatment
WASHINGTON: People who suffer from Parkinson's disease face up to twice the risk of developing deadly skin cancer, an analysis of 12 studies on the topic showed on Monday.

Previous research has shown mixed results, but the meta-analysis by the National Institute of Environmental Health Sciences and published in the journal Neurology showed a significantly higher risk of melanoma in Parkinson's patients.

Men with Parkinson's are twice as likely to develop melanoma, the most dangerous form of skin cancer, and women with Parkinson's were 1.5 times as likely to receive the same diagnosis.

There was no link observed between non-melanoma skin cancer and Parkinson's in the dozen studies which spanned 1965 to 2010.

Since the studies were small in size, most showing fewer than 10 cases of people with both conditions, it was difficult to draw individual conclusions.

However, the meta-analysis showed a distinctly increased risk.

"Parkinson's disease patients in general have a lower risk for cancer, smoking-related cancers in particular, but they may have a higher risk for melanoma," said study author Honglei Chen.

"One possible explanation for the link between Parkinson's and melanoma is that the two diseases may share some genetic or environmental risk factors," Chen said.

"However, our understanding of this link is very preliminary."

Worldwide estimates of the number of people living with Parkinson's, a brain disease that causes physical tremors and difficulty with movement and balance, range from five to 10 million.

About 132,000 melanoma skin cancers occur globally each year, according to the World Health Organization.

- AFP/cc



Taken from ChannelNewsAsia.com; source article is below:
Parkinson's patients show high melanoma risk

Enhanced by Zemanta

Wednesday, February 24, 2010

Drugs to Pass Exams -- Will It Help to Pass Life's Tests, Too?

Diagram of the brain of a person with Alzheime...Image via Wikipedia
UK UNIVERSITIES TO CURB USE WITH DOPE TESTS
-------------------------------------------

LONDON - British universities must investigate measures, including random dope testing, to tackle the increasing use of cognitive enhancement drugs by students for exams, a leading behavioural neuroscientist warns.

Student use of drugs, such as Ritalin and Modafinil, available over the Internet and used to increase the brain's alertness, had "enormous implications for universities", said Dr Barbara Sahakian, a professor of clinical neuropsychology at Cambridge University's psychiatry department.

Normally prescribed for neurological disorders including Alzheimer's disease, attention deficit hyperactivity disorder (ADHD) and narcolepsy, such drugs boost acetylcholine in the brain, improving alertness and attention.

Their use has prompted concerns that they could give students an unfair advantage. "This is something that universities really have to discuss. They should have some strategy, some kind of active policy," Dr Sahakian said.

"The coercion aspect is a strong one. Some students say they feel it is cheating, and it puts pressure on them to feel they have to use these drugs when they don't really want to."

Dr Sahakian, whose work is at the forefront of research on the effects of such drugs on healthy people, said urgent debate was now needed on the ethics of how society dealt with "smart drugs".

Though data on long-term effects on healthy users was not yet available, some scientists believe that pharmaceutical advancement and cultural acceptance could make "cosmetic neurology" as popular as beauty "enhancements".

"If a safe and effective drug is developed which enhances cognition, then I think it would be difficult not to allow access to it," Dr Sahakian said. But if such drugs were then legal, many ethical issues had to be addressed.

"The big question is, are we all going to be taking drugs in the next 10 years and boosting our cognition in that way? And if we are, will we use them to have a shorter working week ... or will we go headlong into a 24/7 society where we work all the time because we can? You have to consider there are things that could be beneficial about such drugs because we have an ageing population," she said.

Surveys in the United States indicate that 16 per cent of university students are using "smart drugs". There are global websites and chatrooms devoted to how to best use drugs to aid study.

A Nature magazine poll of 1,400 respondents - mostly scientists and researchers - indicated that one in five had used "smart drugs".

Questioned about their attitude towards the drugs, the majority frowned on their usage in competitive situations, such as university entrance exams. However, some admitted that they would be pressured to give their child a "smart" drug if other children were using them. THE GUARDIAN

From TODAY, Monday, 22-Feb-2010
----------

Tuesday, June 30, 2009

Double trouble

VISION
Seeing two of a kind may be an indication of more serious problems
Eveline Gan, eveline@mediacorp.com.sg
 
DoubleTrouble More than meets the eye: Seeing double may point to a neurological problem.


It started with a headache and pain around her left eye. A week later, Mdm K began seeing double images.

"I lay in bed the whole day. I couldn't even watch TV because I would see two of everything," said the 61-year-old homemaker.

She initially thought it was a side effect of her on-off headache and wanted to brush it off. Thankfully, her brother insisted on taking her to the hospital.

A scan revealed that the muscles in her left eye had swelled up. Any delay in treatment would have led to more complications.

Certain benign eye conditions such as astigmatism - caused by an irregularly-shaped cornea - can cause you to see double images. So can extreme fatigue or overindulging in alcohol.

But if you start having double vision out of the blue, or if it keeps recurring, then you have every reason to worry.

According to Dr Wang Jenn Chyuan, senior consultant ophthalmologist and medical director of Nobel Eye and Vision Centre at Mt Alvernia Hospital, any visual problem should be taken seriously as it may be caused by more serious medical conditions.

In fact, double vision, or diplopia in medical lingo, is "almost always" one of the symptoms of a host of neurological disorders, added Dr Nagaendran Kandiah, a consultant neurologist at National Neuroscience Institute, Singapore. They include brain tumours, stroke, and diseases affecting the eye muscle and nerves around the eyes.

Being able to see a single image with two eyes is a complex process that involves the brain, muscles and nerves.

Explaining how healthy eyes work, Dr Wang said: "When a person with normal vision looks at an object, the brain and nerves coordinate the alignment of both eyes. This is so that the two images sent to the brain are perfectly superimposed on each other and he sees only one image."

A neurological or muscle problem can cause the eyes to be misaligned, so each has a different focus. When this happens, explained Dr Nagaendran, the brain will misinterpret the images to be in two different locations, causing you to see double.

A DOUBLE WHAMMY

And as if the discomfort of seeing double images isn't bad enough, patients also often experience headaches with their double vision, as in Mdm K's case.

Dr Nagaendran said that the pain may suggest that there is an inflammation or aneurysm - a ballooning of the arteries - in the brain. Eye pain can also occur if the swollen arteries press on the nerves connected to the eye.

TUNING OUT

Sometimes, double vision which has been ignored for a long time may go away without any treatment. It may mean that your brain has learnt to "suppress" one of the images seen by one of the eyes, said Dr Wang.

"It's the body's way of preventing confusion when the mind perceives two different images."

But don't rejoice too soon.

Suppression of one of the images can result in lazy eye. And in the case of a more serious condition such as a brain tumour or aneurysm, ignoring the problem can lead to blindness or death, Dr Wang warned.

In most cases, treating the underlying medical problem will help resolve the double vision.

"As long as there is no irreversible damage to the nerve or brainstem, most symptoms often go away, either partially or completely, in six to 12 weeks," added Dr Nagaendran.

For Mdm K, the prompt anti-inflammatory treatment she got after being diagnosed helped her to regain normal vision.


From TODAY, Health – Tuesday, 30-Jun-2009
In collaboration with Health Promotion Board