Showing posts with label Magnetic resonance imaging. Show all posts
Showing posts with label Magnetic resonance imaging. Show all posts

Thursday, October 23, 2014

When people shop for health care, they save money

Cover of the first issue of Journal of the Ame...
Cover of the first issue of Journal of the American Medical Association. (Photo credit: Wikipedia)
By Peter R. Orszag




If people knew the prices of medical treatments, and if they paid partly from their own pockets, they might shop around and save money.

This stands to reason, and a new study in the Journal of the American Medical Association shows it is true. This comes as very encouraging news for the wider effort to keep going the profound deceleration in health costs we have seen over the past several years.

A team of researchers led by Christopher Whaley of the University of California at Berkeley and Castlight Health examined what happens when hundreds of thousands of people are given access to a website that provides prices for various medical procedures.

Historically, consumers have had difficulty finding out the price they will be charged for a specific procedure or visit. But it is reasonable to expect that if prices were provided, and if the patients had “skin in the game” by cost-sharing, they would seek out lower-priced option.

That is exactly what the researchers found. The use of the price-transparency tool was associated with a 14 percent decline in payments for laboratory tests, a 13 percent decline in payments for advanced imaging test, and a 1 percent decline in payments for clinician office visits. Giving more information to consumers about the prices of their health care, in other words, led them to choose less expensive options.

These encouraging findings come with four important caveats. The first is that although price transparency is a good start, the American health-care system needs to provide better value, not just lower prices.

Little or no evidence links price to quality in health care, so my strong guess is that consumers who choose somewhat lower prices can help to shift the system towards somewhat higher value. But consumers should not have to make such guesses.

The second caveat is that price transparency in concentrated markets may facilitate collusion among providers. The concern is most salient when prices are publicly posted.

The third caveat is that the savings involved in the study were very small. The average lab-test payment reduction, for example, amounted to US$3.45 (S$4.40), and for the clinician office visit, it was US$1.18. The advanced imaging result was larger, at US$125, but still not huge.

This may help explain why so few people consulted the price website – only 6 percent of lab tests were preceded by a price search, for example. It also underscores the limited gains we should expect from price transparency – health-care costs are concentrated among the highest-cost patients. Patients will and should have deep insurance against high cost, constraining the ability of price transparency to have enormous effects on total spending.

The final caveat is that, especially with such small participation rates, one always wonders whether the people using the price website were fundamentally different from non-users in some way.

Despite these cautionary notes, the transparency study is very welcome news in the ongoing effort to produce better value in health care. We should be aggressively expanding efforts like the transparency tools that have helped consumers choose lower-priced options.

BLOOMBERG


Taken from My Paper, Thursday, October 23, 2014


Thursday, August 23, 2012

CT scans in childhood increased cancer risk, says study

Posted: 07 June 2012

A CT scanner
PARIS: Children exposed to multiple CT scans could be up to three times likelier to contract cancer of the blood, brain or bone marrow later in life, according to research published on Thursday.

Writing in The Lancet medical journal, a team of scientists in Canada, Britain and the United States said the cancer risk, in absolute terms, appears to be small.

But they appealed for radiation doses from CT scans to be kept at a minimum and for alternatives to be used where appropriate.

The researchers claimed their study was the first to provide direct evidence of a link between exposure from CT radiation in childhood and later cancer risk.

"Of utmost importance is that where CT is used, it is only used where fully justified from a clinical perspective," said lead author Mark Pearce of Newcastle University's Institute of Health and Society.

As a vital diagnostic technique, use of the CT scan has increased rapidly in the past 10 years, particularly in the United States, the researchers said.

"However, potential cancer risks exist due to the ionising radiation used in CT scans, especially in children who are more radiosensitive than adults."

Computerised tomography - commonly known as CT - is an X-ray technique that produces images of the body's internal structures in cross sections.

The researchers studied nearly 180,000 people who underwent a CT scan as children or young adults (under 22) in Britain between 1985 and 2002.

Of these, 74 were subsequently diagnosed with leukaemia and 135 with brain cancer according to data for the period 1985 to 2008.

The team calculated that compared to patients who received a radiation dose of less than five milli-Grays (mGy), those who were given a cumulative dose of 30 mGy had about three times the risk of developing leukaemia (cancer of the blood or marrow) later in life.

Those who received 50 to 74 mGy had thrice the risk of brain tumours.

The study did not compare children who had been scanned against those who had not been scanned.

Put into context, this means that among every 10,000 patients who received one CT scan before the age of 10, there would be one extra case of leukaemia and one extra brain tumour per 10 mGy of radiation in the 10 years after exposure.

"Further refinements to allow reduction in CT doses should be a priority, not only for the radiology community, but also for manufacturers," said Pearce.

"Alternative diagnostic procedures that do not involve ionising radiation exposure, such as ultrasound and MRI (magnetic resonance imaging) might be appropriate in some clinical settings."

Commenting on the study, Andrew Einstein of the Columbia University Medical Centre in New York said Pearce and his colleagues' work confirmed that CT scans "almost certainly produce a small cancer risk".

"Use of CT scans continues to rise, generally with good clinical reasons, so we must redouble our efforts to justify and optimise every CT scan."

- AFP/de



Taken from ChannelNewsAsia.com; source article is below:
CT scans in childhood increased cancer risk, says study

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Tuesday, March 1, 2011

Do you have a happy gene?

On the Threshold of EternityImage via WikipediaIf genes can be inherited, I would sure like to pass down to my descendants the happy and healthy genes!
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Study finds link between genes and depression
Posted: 08 February 2011

Depression
WASHINGTON - People who are genetically predisposed to produce lower amounts of a certain brain chemical that regulates appetite and stress may be at higher risk of severe depression, researchers said Monday.

The findings should shed more light on how depression affects certain people more than others, and could help lead the way toward developing more individualised therapies, researchers at the University of Michigan said.

"We've identified a biomarker - in this case genetic variation - that is linked with increased risk of major depression," said senior study author Jon-Kar Zubieta, a professor of psychiatry and radiology.

"This appears to be another mechanism, independent of previous targets in depression research, such as serotonin, dopamine and norepinephrine."

People who produce lower amounts of the brain molecule neuropeptide Y (NPY) had "measurably stronger brain responses to negative stimuli and psychological responses to physical pain," the study said.

"They were also overrepresented in a population diagnosed with a major depressive disorder."

The study, which appears in the Archives of General Psychiatry, used three different methods. First, researchers classified subject participants into three categories according to low, medium or high NPY expression.

Then, they used MRI (magnetic resonance imaging) to look at brain activity as the subjects viewed different words -- some neutral (like "material"), some negative (like "murderer") and some positive (like "hopeful").

"In response to negative words, subjects in the low NPY group showed strong activation in the prefrontal cortex, which is involved with processing emotion, while subjects with high NPY demonstrated a much smaller response," the study said.

In the second trial, researchers looked at how subjects described their emotional state before and after a stress challenge in which saline solution was injected into their jaw muscles, causing moderate pain for about 20 minutes.

"Those in the low NPY group were more negative both before and after the pain - meaning they were more emotionally affected while anticipating the pain and while reflecting on their experience immediately afterward," it said.

Finally, researchers examined the NPY genotypes of people with major depressive disorders and found that, compared to a control group, people with low NPY were "overrepresented" in the group with depression.

"These are genetic features that can be measured in any person," said lead author Brian Mickey, an assistant professor in the Department of Psychiatry at the University of Michigan Medical School.

"We hope they can guide us toward assessing an individual's risk for developing depression and anxiety."

- AFP/rl


Taken from ChannelNewsAsia.com; source article is below:
Study finds link between genes and depression



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Tuesday, December 14, 2010

A common blood test's advantage

Once in a while some good things come out of the ordinary, the common... and we rejoice!
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Common blood test could detect heart disease

Surgeons perform a heart surgery.
WASHINGTON: An improved version of a common emergency room blood test could be used to detect heart disease in apparently healthy patients, according to a US study published on Tuesday.

"This test is among the most powerful predictors of death in the general population we've seen so far," said James de Lemos, associate professor of internal medicine at University of Texas Southwestern and lead author of the study.

"It appears that the higher your troponin T, the more likely you are to have problems with your heart, and the worse you're going to do, regardless of your other risk factors."

A less sensitive test for the protein, called cardiac troponin T (cTnT), is already used by ER doctors who want to test whether a patient who is complaining of chest pains is actually experiencing a heart attack.

The new, more sensitised version was able to detect the protein in about 25 percent of samples provided by more than 3,500 people.

It "can detect circulating cTnT levels in almost everyone with chronic heart failure and chronic coronary artery disease," said the study.

"People with detectable levels of troponin T were nearly seven times more likely to die within six years from heart disease," added the study, published in the Journal of the American Medical Association.

The research followed more than 3,500 people from 2000 to 2007. Subjects gave blood samples and submitted to multiple body scans, magnetic resonance imaging (MRI) and computed tomography (sectional imaging) to examine the heart and other organs.

"This study was designed to be representative of urban communities throughout the United States where there is a high prevalence of obesity, untreated hypertension and diabetes - just as there is in Dallas," de Lemos said.

The most elevated levels of cTnT were detected among older adults, men, African-Americans and people who suffered "abnormal thickening or weakness of the heart muscles."

De Lemos said he hoped "in the future to be able to use it to prevent some death and disability from heart failure and other cardiac diseases."

Heart disease in the number one killer of Americans, according to the Centres for Disease Control, which said last year that 785,000 Americans had a new coronary attack, and about 470,000 had a recurrent attack.

- AFP/de


Taken from ChannelNewsAsia.com; source article is below:
Common blood test could detect heart disease



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Sunday, September 5, 2010

Detecting Autism thru Brain Scan

British scientists develop brain scan to detect autism
Teens with autism are seen at a school in Paris
Playing, Laughing and Learning with Children on the Autism Spectrum: A Practical Resource of Play Ideas for Parents and CarersThinking in Pictures (Expanded, Tie-in Edition): My Life with Autism (Vintage)1001 Great Ideas for Teaching and Raising Children with Autism or Asperger's, Revised and Expanded 2nd EditionAutism Spectrum Disorders: The Complete Guide to Understanding Autism, Asperger's Syndrome, Pervasive Developmental Disorder, and Other ASDsTen Things Every Child with Autism Wishes You KnewLONDON: British scientists have developed a 15-minute brain scan they hope could be used to detect autism in children, cutting both the time and cost of diagnosing the disorder.

Researchers from the Institute of Psychiatry at King's College London on Tuesday published details of the technique, which has been tested on adults and shown to have 90 percent accuracy in detecting autism.

Children are presently assessed through a lengthy process that tests social interaction, communication and imaginative skills.

A confirmed diagnosis is rare before 18 months, and most often occurs much later.

Christine Ecker, a member of the institute's research team, said the new tool's benefits could be "immense".

"It could help to alleviate the need for the emotional, time-consuming and expensive diagnosis process which ASD (autism spectrum disorder) patients and families currently have to endure," she said.

"We now look forward to testing if our methods can also help children."

The British scientists hope the new method will be both quicker and up to 20 times more cost effective.

The scans cost between 100 pounds (160 dollars, 120 euros) and 200 pounds, far cheaper than current alternatives in Britain.

The technique assesses structural changes in the brain. It is expected to take more than two years before it is ready to be rolled out for general use.

Autism and related disorders affect up to six or seven out of every 1,000 individuals.

Symptoms are lifelong and can vary widely, but often include impaired social skills, repetitive behaviours, difficulty in expressing one's emotions, and an aversion to physical intimacy. There is no known cure.

The new technique developed by the Institute of Psychiatry researchers involves taking pictures of the brain with a magnetic resonance imaging scanner.

The scans are reconstructed into 3D images and analysed by computer software programmed to spot hallmarks of autism in the structure of different brain areas.

The results of testing the technique on 20 adults with autism and the same number of healthy "control" volunteers were published Tuesday in The Journal of Neuroscience".

All those taking part were men aged between 20 and 68. After first being asked to undergo the conventional diagnostic procedure, each participant had his brain scanned. The outcomes of both techniques were then compared.

The brain scan method was 90 percent accurate in correctly identifying the autistic patients. It also showed a negative result for healthy controls in 80 percent of cases. - AFP/jm


From ChannelNewsAsia.com; source article is below:British scientists develop brain scan to detect autism
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