Showing posts with label Britain. Show all posts
Showing posts with label Britain. Show all posts

Monday, September 6, 2010

Breast cancer deaths in Europe falls

Hopefully, this type of news will be seen daily...
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Study finds fall in breast cancer deaths in Europe
Breast Cancer Husband : How to Help Your Wife (and Yourself) during Diagnosis, Treatment and BeyondBreast Cancer: Real Questions, Real AnswersUplift : Secrets from the Sisterhood of Breast Cancer SurvivorsChicken Soup for the Breast Cancer Survivor's Soul: Stories to Inspire, Support and Heal (Chicken Soup for the Soul)Just Get Me Through This!: The Practical Guide to Breast CancerBreast Cancer Survival Manual, Fourth Edition: A Step-by-Step Guide for the Woman With Newly Diagnosed Breast CancerPARIS: Breast cancer deaths dropped by more than 20 per cent across 15 European countries over the last two decades, with a fall of nearly a third in Britain, according to a study published Thursday.

At the same time, the level of breast cancer mortality in eastern Europe was described as "catastrophic".

The review of 30 countries, overseen by French researchers, found large decreases in the number of women dying from breast cancer, particularly in Britain and Iceland.

Mortality rates across the 30 countries fell by a fifth to 24 per 100,000 deaths, with Spain claiming the lowest rate at 18.9.

Britain's rate per 100,000 deaths fell from 41.6 to 28.2, although it still lags behind countries such as Germany and France.

The study examined World Health Organisation (WHO) data on cancer death rates from 1989 to 2006 alongside information from individual countries.

Researchers at the International Agency for Research on Cancer in Lyon, France, attributed the improvements in Britain to better screening and patient care.

The leader of the study, Philippe Autier, told AFP: "The English were really shocked by their extremely high death rates from breast cancer in the late 1980s, but they took the bull by the horns.

"They have done what they needed to do to succeed and they have grasped that they had to do this in a concerted fashion."

He predicted within three years, Britain -- long considered one of the worst major European countries for surviving breast cancer -- would have a better survival rate for the disease than France.

Death rates in France, Finland, and Sweden, have decreased by 11 per cent, 12 per cent and 16 per cent since the 1980s, but Autier said the results were disappointing considering the investment in cancer care in the three countries.

"There are three countries that really surprised us. There is a real need to review the system."

Autier said France had made "gigantic efforts" in cancer care and carries out four times more screenings for breast cancer than in Britain, so the results pointed to problems in the way the French system was managed.

Turning to countries in eastern Europe, Autier described the situation as "catastrophic".

"Their big problem is that their health system has not been totally modernised... the issues are essentially financial."

In an accompanying editorial, professors Valerie Beral and Richard Peto, from Oxford University, agreed that apparently poor British survival rates were misleading and blamed problems with the way cancers were recorded.

"In contrast with death registration, cancer registration is not statutory in the UK and is known to be somewhat incomplete," they wrote.

"Partly because of this incompleteness, survival calculations based on registry data make UK cancer survival rates seem significantly worse than they really are."

-AFP/wk


From ChannelNewsAsia.com; source article is below:Study finds fall in breast cancer deaths in Europe
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Sunday, September 5, 2010

Superbugs!

New superbugs spreading from South Asia
LONDON - "Health tourists" flocking to south Asia have carried a new class of antibiotic-resistant superbugs to Britain, researchers reported Wednesday, warning that the bacteria could spread worldwide.

Many hospital infections that were already difficult to treat have become even more impervious to drugs due to a recently discovered gene that can jump across different species of bacteria.

This so-called NDM-1 gene was first identified last year by Cardiff University's Timothy Walsh in two types of bacteria -- Klebsiella pneumoniae and Escherichia coli -- in a Swedish patient admitted to hospital in India.

Worryingly, the new NDM-1 bacteria are resistant even to carbapenems, a group of antibiotics often reserved as a last resort for emergency treatment for multi-drug resistant bugs.

Researchers said the bugs had been brought into Britain by patients who travelled to India or Pakistan for cosmetic surgery.

"If these infections were allowed to continue without appropriate treatment, then certainly one would expect to see some sort of mortality," Walsh, a microbiology professor, told BBC radio.

"It's going to be very difficult to treat the infections once the patients present with these types of bacteria. You won't get well."

In the new study, led by Walsh and Madras University's Karthikeyan Kumarasamy, researchers set out to determine how common the NDM-1 producing bacteria were in South Asia and Britain, where several cases had turned up.

Checking hospital patients with suspect symptoms, they found 44 cases -- 1.5 percent of those screened -- in Chennai, and 26 (eight percent of those screened) in Haryana, both in India.

They likewise found the superbug in Bangladesh and Pakistan, as well as 37 cases in Britain, some in patients who had recently returned from having cosmetic surgery in India or Pakistan.

"India also provides cosmetic surgery for other Europeans and Americans, and it is likely that NDM-1 will spread worldwide," said the study, published in British medical journal The Lancet.

NDM-1 was mostly found in E. coli, a common source of community-acquired urinary tract infections, and K. pneumoniae, and was impervious to all antibiotics except two, tigecycline and colistin.

In some cases, even these drugs did not beat back the infection.

"We've actually almost run out of antibiotics. We only have two left and one isn't particularly good," Walsh told the BBC.

Crucially, the NDM-1 gene was found on DNA structures, called plasmids, that can be easily copied and transferred between bacteria, giving the bug "an alarming potential to spread and diversify," the authors said.

"Unprecedented air travel and migration allow bacterial plasmids and clones to be transported rapidly between countries and continents," they said, adding that most could remain undetected.

The emergence of these new drug-resistant strains could become a serious global public health problem as the major threat shifts toward a broad class of bacteria -- including those armed with the NDM-1 gene -- known as "Gram-negative", the researchers warn.

"There are few new anti-Gram-negative antibiotics in development, and none that are effective against NDM-1," the study said.

NDM-1 stands for New Delhi metallo-beta-lactamase-1.

"We believe it's present within the community within India -- not just within the hospitals," Walsh said.

The professor said that looking ahead to what might be available to treat NDM-1, "there are no new antibiotics that are going to be available in 10 years' time".

He added: "We desperately need -- in the 21st century it sounds ridiculous that we don't have -- a globally-funded surveillance system.

"Secondly, there is a desperate need for new and novel antibiotics targeted towards these types of bacteria."

- AFP /ls


From ChannelNewsAsia.com; source article is below:New superbugs spreading from South Asia
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